In premenopausal women, most of the estrogen in the body is made by the ovaries. Because estrogen makes hormone-receptor-positive breast cancers grow, reducing the amount of estrogen in the body or blocking its action can help shrink hormone-receptor-positive breast cancers and reduce the risk of hormone-receptor-positive breast cancers coming back recurring. This is called prophylactic or protective ovary removal, or prophylactic oophorectomy. Removing the ovaries is one way to permanently stop the ovaries from producing estrogen. Medicines also can be used to temporarily stop the ovaries from making estrogen called medical shutdown. Ovarian shutdown with medication or surgical removal is only for premenopausal women.
Risks and causes
Ovarian Shutdown or Removal | ruthann1.com
Breast cancer is the second most common cancer among women, after skin cancer. There are also many things a woman can do to decrease her risk. You may be at high risk of developing breast or ovarian cancer if:. At this clinic, we provide a personalized approach to cancer risk assessment, prevention, and screening, including an evaluation and a discussion of your individual breast and ovarian cancer risk.
Ovarian Shutdown or Removal
Every year, about 20, women in the United States get ovarian cancer. But less than a third do genetic testing, according to a new study published in the Journal of Clinical Oncology. Among women with breast cancer, less than a quarter had genetic testing for cancer-associated mutations. The study involved 83, women in California and Georgia who were diagnosed with breast or ovarian cancer in and
It might feel like your world stops after receiving a diagnosis of breast or ovarian cancer. Even in that mental and emotional fog, there are several next steps to consider. Coming up with a treatment plan is a big one, along with finding out whether or not you need any kind of additional exams, like BRCA testing to look for certain genetic mutations that increase cancer risk. As a result, your cells are more likely to develop more genetic alterations that can eventually lead to cancer. BRCA mutations are involved in 5 to 10 percent of breast cancer cases and about 15 percent of ovarian cancer cases, according to the Mayo Clinic.